Ethylene Glycol

Ethylene Glycol

SCHEMBL1170099

C=CCCCCCCCCCCCCCCCCCCCC.OCCO

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.80
ALDH1A1 P00352 4/20 0.62
LMNA P02545 3/20 0.50
HSD17B10 Q99714 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.46
ABCC4 O15439 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL11578306 1.00 TSHR (0.80) TSHRALDH1A1LMNAHSD17B10MEN1
Ethylene Glycol SCHEMBL5084707 1.00 TSHR (0.80) TSHRALDH1A1LMNAHSD17B10MEN1
Ethylene Glycol SCHEMBL20958140 1.00 TSHR (0.80) TSHRALDH1A1LMNAHSD17B10MEN1
Ethylene Glycol SCHEMBL1881649 1.00 TSHR (0.80) TSHRALDH1A1LMNAHSD17B10MEN1
Ethylene Glycol SCHEMBL1878023 1.00 TSHR (0.80) TSHRALDH1A1LMNAHSD17B10MEN1
Ethylene Glycol SCHEMBL475463 1.00 TSHR (0.80) TSHRALDH1A1LMNAHSD17B10MEN1
Ethylene Glycol SCHEMBL5665434 0.98 TSHR (0.76) TSHRALDH1A1LMNAHSD17B10MEN1
Ethylene Glycol SCHEMBL5666383 0.98 TSHR (0.76) TSHRALDH1A1LMNAHSD17B10MEN1
Ethylene Glycol SCHEMBL2437033 0.97 TSHR (0.75) TSHRALDH1A1LMNAHSD17B10MEN1
Propanol SCHEMBL11193775 0.95 TSHR (0.80) TSHRALDH1A1LMNAHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1594440-B1 THE SELECTIVE AND SPECIFIC PREPARATION OF DISCRETE PEG COMPOUNDS QUANTA BIODESIGN LTD (US) 2019-07-03 EP disclosed
US-8637711-B2 Selective and specific preparation of discrete PEG compounds QUANTA BIODESIGN, LTD. (US) 2014-01-28 US disclosed
US-20110124844-A1 Selective and Specific Preparation of Discrete Peg Compounds AUDAX PRIVATE DEBT LLC, AS AGENT 2011-05-26 US disclosed
US-7888536-B2 Selective and specific preparation of discrete PEG compounds QUANTA BIODESIGN, LTD. (US) 2011-02-15 US disclosed
EP-1594440-A4 THE SELECTIVE AND SPECIFIC PREPARATION OF DISCRETE PEG COMPOUNDS QUANTA BIODESIGN LTD (US) 2006-12-27 EP disclosed
US-20060020134-A1 Selective and specific preparation of discrete peg compounds AUDAX PRIVATE DEBT LLC, AS AGENT 2006-01-26 US disclosed
EP-1594440-A2 THE SELECTIVE AND SPECIFIC PREPARATION OF DISCRETE PEG COMPOUNDS Quanta Biodesign, Ltd. (US) 2005-11-16 EP disclosed
WO-2004073620-A2 THE SELECTIVE AND SPECIFIC PREPARATION OF DISCRETE PEG COMPOUNDS QUANTA BIODESIGN, LTD (US) 2004-09-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124844-A1 Selective and Specific Preparation of Discrete Peg Compounds PARG, GNE, PAM TSHR 3935/4885ALDH1A1 1674/4885LMNA 1964/4885
US-20060020134-A1 Selective and specific preparation of discrete peg compounds PARG, GNE, PAM TSHR 3935/4885ALDH1A1 1674/4885LMNA 1964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.