Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MPI | P34949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11705782 | 0.84 | — | — | |
| SCHEMBL9480123 | 0.79 | — | — | |
| SCHEMBL11707732 | 0.79 | ALDH1A1 (0.39) | ALDH1A1CA1CA2CA4CA5A | |
| SCHEMBL11710091 | 0.79 | ALDH1A1 (0.39) | ALDH1A1CA1CA2CA4CA5A | |
| SCHEMBL11705257 | 0.76 | ALDH1A1 (0.37) | ALDH1A1CA1CA2CA4CA5A | |
| SCHEMBL11709258 | 0.74 | ALDH1A1 (0.36) | ALDH1A1CA1CA2CA4CA5A | |
| SCHEMBL31339479 | 0.71 | ALDH1A1 (0.65) | ALDH1A1CA1CA2CA4CA5A | |
| SCHEMBL12205519 | 0.69 | — | — | |
| SCHEMBL11554365 | 0.67 | — | — | |
| SCHEMBL9509064 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2947075-B1 | SYNTHESIS METHOD OF THIADIAZOLYLAMIDE DERIVATIVE | ZHEJIANG ZHUJI UNITED CHEMICALS CO LTD (CN) | 2016-11-16 | — | — | EP | disclosed |
| EP-2947075-A1 | SYNTHESIS METHOD OF THIADIAZOLYLAMIDE DERIVATIVE | Zhejiang Zhuji United Chemicals Co., Ltd (CN) | 2015-11-25 | — | — | EP | disclosed |
| US-4061645-A | FUNGICIDE, NEMATOCIDE | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |
| US-4005213-A | 2,5-Substituted-1,3,4-thiadiazoles as fungicides | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-01-25 | — | — | US | disclosed |