Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27553396 | 0.84 | IAPP (0.46) | TYRCHRNA7 | |
| SCHEMBL1000871 | 0.83 | HPGD (0.55) | POLBNPSR1HPGDCYP2C19FFAR1 | |
| SCHEMBL10931514 | 0.81 | CAMK2A (0.51) | NPSR1HPGD | |
| SCHEMBL490491 | 0.81 | POLB (0.67) | POLBTYR | |
| SCHEMBL29998634 | 0.81 | POLB (0.67) | POLBTYR | |
| SCHEMBL31424460 | 0.80 | KDM4E (0.46) | POLBNPSR1HPGDCYP2C19FFAR1 | |
| SCHEMBL4885810 | 0.80 | POLB (0.49) | POLBNPSR1TYRCHRNA7FFAR1 | |
| SCHEMBL6888877 | 0.80 | ALDH1A1 (0.43) | POLB | |
| SCHEMBL3652088 | 0.79 | POLB (0.51) | POLBNPSR1TYRCHRNA7FFAR1 | |
| SCHEMBL4374965 | 0.79 | F13A1 (0.44) | POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016033337-A1 | BIOCOMPATIBLE TISSUE GRAFT | THE CLEVELAND CLINIC FOUNDATION (US) | 2016-03-03 | — | — | WO | disclosed |
| US-4044125-A | GLUTAMIC ACID, GLYCINE, ASPARTIC ACID, OR ALANINE HYDROCHLORIDE, LYSINE DIHYDROCHLORIDE | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |