Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11705080 | 1.00 | SLC6A3 (0.40) | SLC6A3SLC2A1NR1I2MEN1KMT2A | |
| SCHEMBL11500415 | 1.00 | SLC6A3 (0.40) | SLC6A3SLC2A1NR1I2MEN1KMT2A | |
| SCHEMBL11702380 | 1.00 | SLC6A3 (0.40) | SLC6A3SLC2A1NR1I2MEN1KMT2A | |
| SCHEMBL11443940 | 1.00 | SLC6A3 (0.40) | SLC6A3SLC2A1NR1I2MEN1KMT2A | |
| SCHEMBL11701801 | 1.00 | SLC6A3 (0.40) | SLC6A3SLC2A1NR1I2MEN1KMT2A | |
| SCHEMBL11706340 | 0.98 | SLC6A3 (0.41) | SLC6A3SLC2A1NR1I2MEN1KMT2A | |
| SCHEMBL20520244 | 0.84 | ESR1 (0.47) | — | |
| SCHEMBL20520271 | 0.84 | ESR1 (0.47) | — | |
| SCHEMBL20520274 | 0.84 | ESR1 (0.47) | — | |
| SCHEMBL20520193 | 0.84 | ESR1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022838-A | 1,1-DIAR-KETONES, NITRIC ACID, WATER | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1977-05-10 | — | — | US | disclosed |