Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11705383 | 1.00 | NPC1 (0.51) | NPC1MEN1KMT2ARAB9ACASP2 | |
| SCHEMBL11704384 | 0.83 | MEN1 (0.49) | NPC1MEN1KMT2ARAB9ACASP2 | |
| SCHEMBL11704358 | 0.83 | MEN1 (0.49) | NPC1MEN1KMT2ARAB9ACASP2 | |
| SCHEMBL2721139 | 0.82 | NPC1 (0.59) | NPC1MEN1KMT2ARAB9ACASP2 | |
| SCHEMBL11704343 | 0.80 | MEN1 (0.49) | NPC1MEN1KMT2ARAB9ACASP2 | |
| SCHEMBL11704347 | 0.80 | MEN1 (0.49) | NPC1MEN1KMT2ARAB9ACASP2 | |
| SCHEMBL15239562 | 0.75 | HIF1A (0.59) | NPC1MEN1KMT2ARAB9ACASP2 | |
| SCHEMBL15239559 | 0.75 | HIF1A (0.59) | NPC1MEN1KMT2ARAB9ACASP2 | |
| SCHEMBL28686352 | 0.75 | MEN1 (0.68) | NPC1MEN1KMT2ARAB9ACASP2 | |
| SCHEMBL16158225 | 0.74 | MEN1 (0.74) | NPC1MEN1KMT2ARAB9ACASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035413-A | ANTIALLERGENS, ANTILIPAEMIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-07-12 | — | — | US | disclosed |
| US-4013719-A | ANTILIPEMIC, ANTIALLERGEN | CIBA-GEIGY CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |
| US-4000183-A | ANTIALLERGENS AND HYPOLIPIDAEMIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-4000144-A | HYPOLIPIDAEMIC AGENTS AND ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-3933835-A | ANTIALLERGENS, HYPOLIPIDAEMIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |