Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.48 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2721139 | 0.83 | NPC1 (0.59) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL21628735 | 0.81 | KMT2A (0.61) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL30475196 | 0.79 | LMNA (0.58) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL11701921 | 0.79 | MEN1 (0.74) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL16385101 | 0.78 | LMNA (0.62) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL27845478 | 0.77 | LMNA (0.61) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL2763437 | 0.77 | LMNA (0.77) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL12128714 | 0.76 | MEN1 (0.52) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL12746127 | 0.76 | NPC1 (0.52) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL1083023 | 0.76 | MEN1 (0.76) | MEN1KMT2ARAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113811300-A | Novel small molecule inhibitors of TEAD transcription factor | 总医院公司 | 2021-12-17 | — | — | CN | disclosed |