Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10761111 | 0.83 | LMNA (0.46) | RAB9ASMN1; SMN2NPC1HPGDPKM | |
| SCHEMBL10739582 | 0.79 | LMNA (0.51) | RAB9ASMN1; SMN2NPC1HPGDPKM | |
| SCHEMBL15550992 | 0.78 | LMNA (0.56) | RAB9ASMN1; SMN2NPC1HPGDPKM | |
| SCHEMBL6622313 | 0.76 | POLB (0.60) | RAB9ASMN1; SMN2NPC1HPGDPKM | |
| SCHEMBL251109 | 0.76 | LMNA (0.53) | RAB9ASMN1; SMN2NPC1HPGDPKM | |
| SCHEMBL4615092 | 0.76 | LMNA (0.49) | RAB9ASMN1; SMN2NPC1HPGDPKM | |
| SCHEMBL9159918 | 0.76 | SMN1; SMN2 (0.50) | RAB9ASMN1; SMN2NPC1HPGDPKM | |
| SCHEMBL9162960 | 0.73 | LMNA (0.60) | RAB9ASMN1; SMN2HPGDKDM4EKMT2A | |
| SCHEMBL5036507 | 0.73 | CYP1A2 (0.49) | RAB9ASMN1; SMN2NPC1HPGDPKM | |
| SCHEMBL10925258 | 0.72 | BCHE (0.48) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011236-A | N-(BENZIMIDAZOL-2-YL)ARYLCARBOXAMIDES AS ULTRAVIOLET (UV) LIGHT ABSORBERS | MERCK & CO., INC. (US) | 1977-03-08 | — | — | US | disclosed |