SCHEMBL1170549

SCHEMBL1170549

CCCCCNc1ccccc1N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.46
HDAC3 O15379 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
NCOR2 Q9Y618 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
KCNH3 Q9ULD8 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
CNR2 P34972 4/20 0.42
SIGMAR1 Q99720 1/20 0.42
CNR1 P21554 1/20 0.41
PRSS1 P07477 4/20 0.41
CHRM2 P08172 1/20 0.41
MAPT P10636 2/20 0.41
HTT P42858 1/20 0.41
S1PR2 O95136 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29922455 1.00 TLR8 (0.49) TLR8L3MBTL1HDAC3HDAC1HDAC2
SCHEMBL8088625 0.98 L3MBTL1 (0.48) TLR8L3MBTL1HDAC3HDAC1HDAC2
SCHEMBL7970465 0.98 L3MBTL1 (0.48) TLR8L3MBTL1HDAC3HDAC1HDAC2
SCHEMBL29922776 0.98 L3MBTL1 (0.48) TLR8L3MBTL1HDAC3HDAC1HDAC2
SCHEMBL8082845 0.98 L3MBTL1 (0.48) TLR8L3MBTL1HDAC3HDAC1HDAC2
SCHEMBL9168077 0.98 L3MBTL1 (0.48) TLR8L3MBTL1HDAC3HDAC1HDAC2
SCHEMBL7365605 0.98 L3MBTL1 (0.48) TLR8L3MBTL1HDAC3HDAC1HDAC2
SCHEMBL9011310 0.98 L3MBTL1 (0.48) TLR8L3MBTL1HDAC3HDAC1HDAC2
SCHEMBL21799596 0.98 L3MBTL1 (0.48) TLR8L3MBTL1HDAC3HDAC1HDAC2
SCHEMBL29922655 0.98 L3MBTL1 (0.48) TLR8L3MBTL1HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110194984-A Graft polymers with dust treatment characteristic 雅富顿化学公司 2019-09-03 CN claimed
CN-110198957-A The functionalization and its composition in situ of polysaccharide 纳幕尔杜邦公司 2019-09-03 CN claimed
CN-110191942-A Multi-functional olefin copolymer and lubricating composition containing it 雅富顿化学公司 2019-08-30 CN claimed
CN-109705956-A Enhance the dispersant viscosity index improvers of the abrasion protection of engine oil 雅富顿化学公司 2019-05-03 CN claimed
CN-109554943-A A kind of wear-resisting mine fireproof hawser and its processing method 山东莱威新材料有限公司 2019-04-02 CN claimed
CN-108807821-A Isolation film and electrochemical appliance 宁德新能源科技有限公司 2018-11-13 CN claimed
CN-108291171-A The collaboration lubricant oil composite of mixture containing olefin copolymer dispersant type viscosity improver and amine compounds 雪佛龙奥伦耐有限责任公司 2018-07-17 CN claimed
CN-105237883-B A kind of preparation method of cable insulation material 昆山周氏电业有限公司 2018-06-26 CN claimed
CN-107573708-A A kind of composite modified pitch 中铁七局集团第三工程有限公司 2018-01-12 CN claimed
CN-102017214-B Organic thin film for infrared detection UNIV MICHIGAN 2014-03-19 CN claimed
CN-102017214-A Organic thin film for infrared detection UNIV MICHIGAN 2011-04-13 CN claimed
EP-0461774-B1 Dispersant, antioxidant and VI improver and lubricating oil composition containing same TEXACO DEVELOPMENT CORP (US) 1993-12-29 EP claimed
US-4455436-A WHITENERS CIBA-GEIGY CORPORATION (US) 1984-06-19 US claimed
JP-57126454-A None JP disclosed
EP-3623398-B1 RESIN COMPOSITION COMPRISING A MODIFIED BLOCK COPOLYMER AND METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER ASAHI CHEMICAL IND (JP) 2024-08-28 EP disclosed
EP-4201935-A1 CRYSTAL OF COMPOUND X7 HYDROCHLORIDE, PREPARATION METHOD THEREFOR AND USE THEREOF Liaoning Original Drug Center Life Science Research Co., Ltd (CN) 2023-06-28 EP disclosed
US-4015012-A ANTHELMINTICS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed
US-4009994-A Process and product of optical brightening with quaternized benzofuranyl-benzimidazoles CIBA-GEIGY CORPORATION (US) 1977-03-01 US disclosed
US-3970699-A 4-Acylaminophenylacetamidines and a method for their preparation BAYER AKTIENGESELLSCHAFT (DT) 1976-07-20 US disclosed
US-3940417-A Quaternised benzofuranyl-benzimidazoles CIBA-GEIGY CORPORATION (US) 1976-02-24 US disclosed