Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214966 | 0.86 | PTPRC (0.59) | PTPRCTSHRLMNAALDH1A1ACHE | |
| SCHEMBL9734076 | 0.82 | PTPRC (0.63) | PTPRCTSHRLMNAALDH1A1ACHE | |
| SCHEMBL3081516 | 0.82 | TSHR (0.61) | PTPRCTSHRLMNAALDH1A1ACHE | |
| SCHEMBL31496742 | 0.82 | PTPRC (0.63) | PTPRCTSHRLMNAALDH1A1ACHE | |
| SCHEMBL179286 | 0.82 | PTPRC (0.63) | PTPRCTSHRLMNAALDH1A1ACHE | |
| SCHEMBL14744311 | 0.80 | PTPRC (0.61) | PTPRCTSHRLMNAALDH1A1ACHE | |
| SCHEMBL28549165 | 0.80 | PTPRC (0.61) | PTPRCTSHRLMNAALDH1A1ACHE | |
| Dinitrophenylene SCHEMBL27624202 | 0.79 | TSHR (0.85) | PTPRCTSHRLMNAALDH1A1ACHE | |
| SCHEMBL5804180 | 0.79 | PTPRC (0.56) | PTPRCTSHRLMNAALDH1A1ACHE | |
| SCHEMBL14292542 | 0.79 | PTPRC (0.59) | PTPRCTSHRLMNAALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064239-A | LIVER FLUKES | MERCK & CO., INC. (US) | 1977-12-20 | — | — | US | disclosed |