Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PTPRC | P08575 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10907252 | 0.85 | TSHR (0.57) | TSHRLMNAALDH1A1TDP1PTPRC | |
| SCHEMBL11214966 | 0.85 | PTPRC (0.59) | TSHRLMNAALDH1A1TDP1PTPRC | |
| SCHEMBL11655279 | 0.83 | TSHR (0.55) | TSHRLMNAALDH1A1TDP1PTPRC | |
| SCHEMBL11726736 | 0.83 | TSHR (0.55) | TSHRLMNAALDH1A1TDP1PTPRC | |
| SCHEMBL10949253 | 0.82 | TSHR (0.53) | TSHRLMNAALDH1A1TDP1PTPRC | |
| SCHEMBL11705641 | 0.82 | PTPRC (0.56) | TSHRLMNAALDH1A1TDP1PTPRC | |
| SCHEMBL11706327 | 0.82 | TSHR (0.53) | TSHRLMNAALDH1A1TDP1PTPRC | |
| SCHEMBL4457412 | 0.82 | TSHR (0.64) | TSHRLMNAALDH1A1TDP1PTPRC | |
| SCHEMBL11691192 | 0.81 | TSHR (0.57) | TSHRLMNAALDH1A1TDP1PTPRC | |
| Dinitrophenylene SCHEMBL27624202 | 0.81 | TSHR (0.85) | TSHRLMNAALDH1A1TDP1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120310010-A1 | Method for producing sulfonamides | BASF SE (DE) | 2012-12-06 | — | — | US | claimed |
| US-20100228054-A1 | Method for Producing Sulfonamides | BASF SE (DE) | 2010-09-09 | — | — | US | claimed |
| EP-1957443-A2 | METHOD FOR PRODUCING SULFONAMIDES | BASF SE (DE) | 2008-08-20 | — | — | EP | claimed |
| WO-2007063028-A2 | METHOD FOR PRODUCING SULFONAMIDES | BASF SE (DE) | 2007-06-07 | — | — | WO | claimed |
| US-4582935-A | REACTING META-NITROBENZOTRICHLORIDE WITH HYDROGEN FLUORIDE IN PRESENCE OF AMMONIUM IONS AND METAL CATALYST | OLIN CORPORATION (US) | 1986-04-15 | — | — | US | claimed |
| CN-103182165-B | Golf | DUNLOP SPORTS CO., LTD. (JP) | 2015-10-28 | — | — | CN | disclosed |
| CN-102989132-B | Golf ball | DUNLOP SPORTS CO LTD | 2015-06-10 | — | — | CN | disclosed |
| US-8912319-B2 | Synthesis of 2′-deoxy-2′-[18F]fluoro-5-methyl-1-B-D-arabinofuranosyluracil (18F-FMAU) | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-12-16 | — | — | US | disclosed |
| EP-2784055-A1 | Fluoroform synthesis and uses thereof in the preparation of trifluoromethylated compounds | Institut National des Sciences Appliquées de Rouen (INSA) (FR) | 2014-10-01 | — | — | EP | disclosed |
| CN-103182165-A | Golf ball | DUNLOP SPORTS CO LTD | 2013-07-03 | — | — | CN | disclosed |
| CN-102989132-A | Golf ball | DUNLOP SPORTS CO LTD | 2013-03-27 | — | — | CN | disclosed |
| US-20120310010-A1 | Method for producing sulfonamides | BASF SE (DE) | 2012-12-06 | — | — | US | disclosed |
| US-4582935-A | REACTING META-NITROBENZOTRICHLORIDE WITH HYDROGEN FLUORIDE IN PRESENCE OF AMMONIUM IONS AND METAL CATALYST | OLIN CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| US-4453012-A | REACTION OF A HALO OR TRIHALOMETHYL BENZENE WITH A TRIHALOMETHYLATED ALIPHATIC OR AROMATIC COMPOUND | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-06-05 | — | — | US | disclosed |
| US-4438043-A | Process for preparation of di- or trifluoromethoxyphenyl ketones or di- or trifluoromethylthiophenyl ketones | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-20 | — | — | US | disclosed |
| EP-0092628-A1 | Process for the preparation of phenyl ketones starting from halogen or trihalogen methyl benzenes and aliphatic or aromatic trihalogen-methyl compounds | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-11-02 | — | — | EP | disclosed |
| EP-0092627-A1 | Process for the preparation of di- or trifluoromethoxyphenyl ketones or of di- or trifluoromethylthiophenyl ketones | RHONE-POULENC CHIMIE (FR) | 1983-11-02 | — | — | EP | disclosed |
| US-4393257-A | NONCATLYTIC REACTION OF CORRESPONDING BENZOTRICHLORIDE WITH HYDROGEN FLUORIDE | DAIKIN KOGYO CO., LTD. (JP) | 1983-07-12 | — | — | US | disclosed |
| US-4163753-A | FROM AN ALIPHATIC ACID ANHYDRIDE AND A TRICHLOROMETHYL AROMATIC COMPOUND | Diaz Chemical Corporation (US) | 1979-08-07 | — | — | US | disclosed |
| US-4046656-A | Photochlorination process for methyl aromatic compounds | THE DOW CHEMICAL COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100228054-A1 | Method for Producing Sulfonamides | STS, MSRB3, SQOR | TSHR 2971/4885LMNA 2425/4885ALDH1A1 1345/4885 |
| US-20120310010-A1 | Method for producing sulfonamides | MSRB3, STS, TST | TSHR 3116/4885LMNA 2543/4885ALDH1A1 2610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.