Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL21817648 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6250717 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL284899 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1697622 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL8388552 | 0.86 | — | — | |
| Bicarbonate SCHEMBL11823002 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL21951326 | 0.86 | — | — | |
| Bicarbonate SCHEMBL20604683 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL21951320 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL48349 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119529642-A | Preparation process of nano-pore aerogel heat-insulating coating | 无锡市明江保温材料有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-119118509-A | Preparation and melting method of radiation-resistant neutral boron-silicon medical special glass container material | 德州晶华药用玻璃有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-113724902-B | Portable heat pipe reactor collision avoidance system | 东南大学 | 2024-11-29 | — | — | CN | claimed |
| CN-118603705-A | Hierarchical analysis method for boron in different forms in soil | 临沂大学 | 2024-09-06 | — | — | CN | claimed |
| CN-118561648-A | Aluminum-based boron oxide doped aluminum thermal energy-containing device | 长江师范学院 | 2024-08-30 | — | — | CN | claimed |
| CN-118240456-A | Nano-pore aerogel heat insulation coating and preparation method thereof | 河北中增智能科技有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-112774249-B | Manufacturing method of miniaturized microwave solid-liquid microextraction device | 云南民族大学 | 2024-04-05 | — | — | CN | claimed |
| CN-117344382-A | Compound alkali metal borophosphate and alkali metal borophosphate nonlinear optical crystal, and preparation method and application thereof | 天津理工大学 | 2024-01-05 | — | — | CN | claimed |
| CN-220272159-U | System for preventing nuclide leakage of vehicle-mounted heat pipe reactor under accident condition | 东南大学 | 2023-12-29 | — | — | CN | claimed |
| US-20230416093-A1 | Compounds Alkali Metal Borophosphates, Alkali Metal Borophosphates Nonlinear Optical Crystals as well as Preparation Method and Application thereof | TIANJIN UNIVERSITY OF TECHNOLOGY (CN) | 2023-12-28 | — | — | US | claimed |
| US-20110027557-A1 | SOLVENT BASED ENVIRONMENTAL BARRIER COATINGS FOR HIGH TEMPERATURE CERAMIC COMPONENTS | GENERAL ELECTRIC COMPANY | 2011-02-03 | — | — | US | claimed |
| US-20110027470-A1 | METHODS FOR MAKING ENVIRONMENTAL BARRIER COATINGS USING SINTERING AIDS | GENERAL ELECTRIC COMPANY | 2011-02-03 | — | — | US | claimed |
| US-20110027484-A1 | METHODS FOR MAKING ENVIRONMENTAL BARRIER COATINGS USING SINTERING AIDS | GENERAL ELECTRIC COMPANY | 2011-02-03 | — | — | US | claimed |
| US-20110027517-A1 | METHODS OF IMPROVING SURFACE ROUGHNESS OF AN ENVIRONMENTAL BARRIER COATING AND COMPONENTS COMPRISING ENVIRONMENTAL BARRIER COATINGS HAVING IMPROVED SURFACE ROUGHNESS | GENERAL ELECTRIC COMPANY | 2011-02-03 | — | — | US | claimed |
| US-20110027578-A1 | WATER BASED SLURRY COMPOSITIONS FOR MAKING ENVIRONMENTAL BARRIER COATINGS AND ENVIRONMENTAL BARRIER COATINGS COMPRISING THE SAME | GENERAL ELECTRIC COMPANY | 2011-02-03 | — | — | US | claimed |
| US-20110027558-A1 | SOLVENT BASED SLURRY COMPOSITIONS FOR MAKING ENVIRONMENTAL BARRIER COATINGS AND ENVIRONMENTAL BARRIER COATINGS COMPRISING THE SAME | GENERAL ELECTRIC COMPANY | 2011-02-03 | — | — | US | claimed |
| US-20110027559-A1 | WATER BASED ENVIRONMENTAL BARRIER COATINGS FOR HIGH TEMPERATURE CERAMIC COMPONENTS | GENERAL ELECTRIC COMPANY | 2011-02-03 | — | — | US | claimed |
| CN-101287680-A | Submicron rare earth borate, preparation method thereof and application thereof as luminescent material | RHODIA OPERATIONS (FR) | 2008-10-15 | — | — | CN | claimed |
| US-20060183011-A1 | Solid polymer electrolyte composite membrane comprising porous ceramic support | PLUG POWER, INC. | 2006-08-17 | — | — | US | claimed |
| WO-1989004735-A1 | PROCESS OF PREPARING SINTERED SHAPES CONTAINING REINFORCEMENT | CERAMICS PROCESS SYSTEMS CORPORATION (US) | 1989-06-01 | — | — | WO | claimed |