Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL8388552 | 0.86 | — | — | |
| Bicarbonate SCHEMBL1170568 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL367438 | 0.86 | — | — | |
| Bicarbonate SCHEMBL551759 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL21951326 | 0.86 | — | — | |
| Bicarbonate SCHEMBL24341 | 0.86 | — | — | |
| Bicarbonate SCHEMBL18155 | 0.86 | — | — | |
| Bicarbonate SCHEMBL20604683 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL21951320 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL25 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12582975-B2 | Method of forming a catalyst article on a substrate | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2026-03-24 | — | — | US | claimed |
| CN-119695504-A | Electromagnetic metamaterial applicable to high-voltage direct-current transmission line and preparation method thereof | 湖北省超能电力有限责任公司 | 2025-03-25 | — | — | CN | claimed |
| CN-119361633-A | High-entropy graphite composite negative electrode material, preparation method thereof, negative electrode and lithium ion battery | 北京理工大学重庆创新中心 | 2025-01-24 | — | — | CN | claimed |
| CN-119140083-A | Monoatomic catalyst for synthesizing cyclic carbonate, and preparation method and application thereof | 中国科学院过程工程研究所 | 2024-12-17 | — | — | CN | claimed |
| CN-114975987-B | Nickel niobate negative electrode material and preparation method and application thereof | 武汉科技大学 | 2024-11-19 | — | — | CN | claimed |
| CN-118125511-A | Doped ternary positive electrode material, preparation method thereof and lithium battery | 天津国安盟固利新材料科技股份有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-117254019-B | Nickel niobate negative electrode material, nickel lithium niobate battery and application thereof | 深圳市谷口科技有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-117983178-A | Preparation method of self-excited perovskite-based composite lithium ion sieve | 中国地质大学（北京） | 2024-05-07 | — | — | CN | claimed |
| CN-117800305-A | Modified lithium iron phosphate material, preparation method thereof, positive electrode plate and secondary battery | 深圳市德方纳米科技股份有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117658618-A | Preparation method and application of europium ion activated phosphate luminescent ceramic | 江苏师范大学 | 2024-03-08 | — | — | CN | claimed |
| EP-3919165-A1 | METHOD FOR FORMING A CATALYST ARTICLE | Johnson Matthey Public Limited Company (GB) | 2021-12-08 | — | — | EP | claimed |
| WO-2021220010-A1 | METHOD OF FORMING A CATALYST ARTICLE | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2021-11-04 | — | — | WO | claimed |
| US-20210339234-A1 | METHOD | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2021-11-04 | — | — | US | claimed |
| CN-108014821-B | Catalyst for synthesizing polyether amine and preparation method and application thereof | 万华化学集团股份有限公司 | 2020-09-08 | — | — | CN | claimed |
| CN-110898794-A | Preparation method of lithium ion sieve | 中国科学院青海盐湖研究所 | 2020-03-24 | — | — | CN | claimed |
| US-6803028-B2 | Method of making stoichiometric lithium niobate | CORNING INCORPORATED | 2004-10-12 | — | — | US | claimed |
| WO-2003087442-A1 | METHOD OF MAKING STOICHIOMETRIC LITHIUM NIOBATE | CORNING INCORPORATED (US) | 2003-10-23 | — | — | WO | claimed |
| US-20030190132-A1 | Method of making stoichiometric lithium niobate | CORNING INCORPORATED | 2003-10-09 | — | — | US | claimed |
| US-6024622-A | Field emission type emitter | SONY CORPORATION (JP) | 2000-02-15 | — | — | US | claimed |
| US-5942202-A | COMPRISING A SMALL AMOUNT OF METAL ELEMENT, E.G., TANTALUM, ZIRCONIUM, AND NIOBIUM; EXCELLENT STORAGE STABILITY AND HEAT STABILITY | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1999-08-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12582975-B2 | Method of forming a catalyst article on a substrate | SCO2, CA4, CA2 | CA4 2/4885CA1 20/4885FAHD1 3609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.