Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27749271 | 0.87 | TP53 (0.53) | MEN1KMT2AUSP2PABPC1KDM4E | |
| SCHEMBL11707284 | 0.86 | CLCN2 (0.47) | MEN1KMT2AKDM4ESMN1; SMN2KDM4C | |
| SCHEMBL5012000 | 0.84 | HTT (0.56) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5253749 | 0.82 | GFER (0.61) | MEN1KMT2AUSP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL11711434 | 0.82 | MEN1 (0.46) | MEN1KMT2AKDM4ESMN1; SMN2GAA | |
| SCHEMBL11709383 | 0.81 | SMN1; SMN2 (0.49) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27728861 | 0.80 | KMT2A (0.51) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL27617932 | 0.79 | MAPK1 (0.56) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5469997 | 0.78 | SMN1; SMN2 (0.47) | MEN1KMT2AKDM4ESMN1; SMN2KDM4C | |
| SCHEMBL11713401 | 0.76 | KDM4E (0.48) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013665-A | ANTIVIRAL, SUBSTITUTED 1,3-DIMETHYL-1H-PYRAZOLO(3,4B)QUINOLINES | BRISTOL-MYERS COMPANY (US) | 1977-03-22 | — | — | US | disclosed |