Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27728861 | 0.90 | KMT2A (0.51) | TP53MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL11706158 | 0.87 | MEN1 (0.53) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL27728859 | 0.83 | ALDH1A1 (0.65) | TP53MEN1KMT2AHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL27749316 | 0.82 | ALDH1A1 (0.63) | TP53MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL27728860 | 0.78 | HTT (0.57) | TP53MEN1KMT2AHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL27729053 | 0.77 | HTT (0.56) | TP53MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL27749269 | 0.75 | TP53 (0.43) | TP53MEN1KMT2AHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL27749272 | 0.74 | TP53 (0.42) | TP53MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL11707284 | 0.74 | CLCN2 (0.47) | MEN1KMT2APOLBSMN1; SMN2HTT | |
| SCHEMBL11711434 | 0.72 | MEN1 (0.46) | TP53MEN1KMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100448869-C | Anilinopyrazole derivatives for the treatment of diabetes | BAYER PHARMACEUTICALS CORP (US) | 2009-01-07 | — | — | CN | claimed |