Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 8/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2457698 | 0.98 | ACHE (0.46) | ACHEBCHEPYCR1TMEM97SIGMAR1 | |
| SCHEMBL12632249 | 0.85 | LSS (0.49) | PYCR1SMN1; SMN2ALDH1A1PTPN1HDAC1 | |
| SCHEMBL11705126 | 0.84 | SMN1; SMN2 (0.46) | ACHEBCHETMEM97SIGMAR1SMN1; SMN2 | |
| SCHEMBL11714658 | 0.83 | ACHE (0.43) | ACHEBCHEPYCR1TMEM97SIGMAR1 | |
| SCHEMBL11715076 | 0.83 | ACHE (0.43) | ACHEBCHEPYCR1TMEM97SIGMAR1 | |
| SCHEMBL11655940 | 0.83 | HDAC6 (0.47) | ACHEPYCR1SMN1; SMN2ALDH1A1PTPN1 | |
| Hydrochloric Acid SCHEMBL11703195 | 0.83 | SMN1; SMN2 (0.48) | ACHEBCHETMEM97SIGMAR1SMN1; SMN2 | |
| SCHEMBL11754169 | 0.82 | ACHE (0.61) | ACHEBCHE | |
| Hydrochloric Acid SCHEMBL11651072 | 0.81 | HDAC6 (0.46) | ACHEPYCR1SMN1; SMN2ALDH1A1PTPN1 | |
| Hydrochloric Acid SCHEMBL11759163 | 0.81 | ACHE (0.59) | ACHEBCHESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035494-A | HYPOLIPIDEMIC AGENTS | SANDOZ, INC. (US) | 1977-07-12 | — | — | US | disclosed |
| US-4035494-A | HYPOLIPIDEMIC AGENTS | SANDOZ, INC. (US) | 1977-07-12 | — | — | US | disclosed |