Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 5/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119196 | 0.83 | LOXL2 (0.64) | LOXL2AGXTHTR2BHTR1ACYP19A1 | |
| SCHEMBL28087518 | 0.80 | LOXL2 (0.46) | LOXL2AGXTHTR2BHTR1ACYP19A1 | |
| SCHEMBL6001322 | 0.79 | LOXL2 (0.42) | LOXL2AGXTHTR2BHTR1ACYP19A1 | |
| SCHEMBL6001333 | 0.77 | LOXL2 (0.43) | LOXL2AGXTHTR2BHTR1AESR1 | |
| SCHEMBL3677391 | 0.76 | LOXL2 (0.42) | LOXL2AGXTHTR2BHTR1ACYP19A1 | |
| SCHEMBL7947099 | 0.74 | KDM4E (0.54) | SMN1; SMN2L3MBTL1PTPN1 | |
| SCHEMBL13561867 | 0.74 | PIM1 (0.38) | LOXL2L3MBTL1 | |
| SCHEMBL10411287 | 0.73 | ESR1 (0.43) | LOXL2AGXTSMN1; SMN2ESR1ESR2 | |
| SCHEMBL14232574 | 0.72 | CYP2A6 (0.39) | LOXL2SMN1; SMN2 | |
| SCHEMBL11712601 | 0.72 | MAOB (0.41) | LOXL2AGXTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002423-A | Benzofuran derivatives process for their preparation and their use as optical brighteners | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-01-11 | — | — | US | disclosed |