SCHEMBL11707367

SCHEMBL11707367

CCCc1c(Cl)c(Cl)c(O)c(Cl)c1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.45
HPGD P15428 5/20 0.45
HSD17B10 Q99714 4/20 0.45
ALDH1A1 P00352 2/20 0.45
MEN1 O00255 2/20 0.45
LMNA P02545 2/20 0.45
MAPT P10636 2/20 0.45
KMT2A Q03164 2/20 0.45
CYP1A2 P05177 5/20 0.40
CYP2C9 P11712 4/20 0.40
HIF1A Q16665 4/20 0.40
MAPK1 P28482 2/20 0.40
CYP2C19 P33261 2/20 0.37
TYMP P19971 1/20 0.34
CFTR P13569 2/20 0.33
CYP3A4 P08684 2/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
CASP1 P29466 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5589670 0.85 HPGD (0.35) TSHRHPGDHSD17B10ALDH1A1MEN1
SCHEMBL5588282 0.85 TSHR (0.41) TSHRHPGDHSD17B10ALDH1A1MEN1
SCHEMBL27558931 0.80 LDHA (0.33) HPGDALDH1A1MAPK1TYMPCFTR
SCHEMBL5589567 0.78 HPGD (0.42) HPGDHSD17B10ALDH1A1LMNAMAPK1
SCHEMBL10584330 0.78 TSHR (0.50) TSHRHPGDHSD17B10ALDH1A1MEN1
SCHEMBL5588136 0.77 LDHA (0.35) CYP2C9HIF1ACYP2C19TYMPCFTR
SCHEMBL28235179 0.76 TSHR (0.47) TSHRHPGDHSD17B10ALDH1A1MEN1
SCHEMBL5589201 0.75 LDHA (0.33) HPGDALDH1A1TYMPCFTRKDM4E
SCHEMBL5586688 0.75 LDHA (0.49) TYMPLDHALDHBMCL1
SCHEMBL17176922 0.74 LDHA (0.41) HPGDALDH1A1CYP1A2CYP2C9MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100500734-C Method for making copolycarbonates GEN ELECTRIC (NL) 2009-06-17 CN claimed
CN-1732203-A Method for making copolycarbonates GEN ELECTRIC (US) 2006-02-08 CN claimed
US-4065517-A POLYPHOSPHONATES NISSAN CHEMICAL INDUSTRIES LTD. (JA) 1977-12-27 US claimed
CN-112313277-B Polyethylene with polycarbonate-siloxane for improved environmental stress cracking resistance SABIC环球技术有限责任公司 2023-06-13 CN disclosed
CN-113166500-A Polyethylene with additives for increasing environmental stress crack resistance SABIC环球技术有限责任公司 2021-07-23 CN disclosed
CN-108463481-B Method for producing polycarbonate 国际壳牌研究有限公司 2021-04-09 CN disclosed
CN-112313277-A Polyethylene with polycarbonate-siloxane for improved environmental stress crack resistance SABIC环球技术有限责任公司 2021-02-02 CN disclosed
CN-108473672-B Process for preparing melt polycarbonate 国际壳牌研究有限公司 2020-12-08 CN disclosed
CN-107580543-A System and method for the reactive ink jet printing of makrolon 沙特基础工业全球技术有限公司 2018-01-12 CN disclosed
CN-104007505-B Light guiding film, ultrathin LCD backlight unit and portable computer 惠和株式会社 2017-07-18 CN disclosed
CN-106046735-A Polycarbonate resin composition with high haze and high light transmittance, and preparation method thereof 中国石油化工股份有限公司 2016-10-26 CN disclosed
CN-101056913-A Process to make polycarbonate from bismethylsalicylcarbonate (BMSC) GEN ELECTRIC (US) 2007-10-17 CN disclosed
CN-101050275-A Method and apparatus to make high molecular weight melt polycarbonate GEN ELECTRIC (US) 2007-10-10 CN disclosed
CN-1972982-A Method for preparing a polycarbonate oligomer mixture at low temperature for manufacturing polycarbonate GEN ELECTRIC (US) 2007-05-30 CN disclosed
CN-1919894-A Copolyetherimides GEN ELECTRIC (US) 2007-02-28 CN disclosed
CN-1914248-A Process for the production of copolycarbonates with reduced color GEN ELECTRIC (US) 2007-02-14 CN disclosed
CN-1732203-A Method for making copolycarbonates GEN ELECTRIC (US) 2006-02-08 CN disclosed
CN-1694914-A Method and apparatus for preparing high molecular weight melt polycarbonate GEN ELECTRIC (US) 2005-11-09 CN disclosed
CN-1383450-A Antibody molecule with specificity to human tumor necrosis factor alpha and application thereof CELLTECH R&D LTD (GB) 2002-12-04 CN disclosed
US-4065517-A POLYPHOSPHONATES NISSAN CHEMICAL INDUSTRIES LTD. (JA) 1977-12-27 US disclosed