Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.56 |
| ▸ | LTA4H | P09960 | 4/20 | 0.55 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568562 | 0.87 | PPARA (0.67) | EPHX2LTA4HPPARAPKMKDM4E | |
| SCHEMBL10305308 | 0.86 | MAPT (0.51) | PPARAMAPTLMNAPKMKDM4E | |
| SCHEMBL11708530 | 0.86 | PPARA (0.58) | PPARAMAPTPKMKDM4EABCB11 | |
| SCHEMBL11709536 | 0.84 | PPARA (0.54) | PPARAMAPTPKMKDM4EABCB11 | |
| SCHEMBL3288292 | 0.84 | PPARA (0.57) | PPARAMAPTKDM4EABCB11CYP1A2 | |
| SCHEMBL11769439 | 0.83 | STS (0.54) | PPARAMAPTABCB11CYP1A2CYP3A4 | |
| SCHEMBL8769001 | 0.83 | GLA (0.54) | PPARAMAPTLMNAKDM4EABCB11 | |
| SCHEMBL11711918 | 0.82 | KDM4E (0.50) | PPARAMAPTLMNAPKMKDM4E | |
| SCHEMBL11766687 | 0.82 | MMP1 (0.56) | PPARAMAPTLMNAPPARGALDH1A1 | |
| SCHEMBL11766693 | 0.82 | MMP1 (0.56) | PPARAMAPTLMNAPPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010279-A | BIPHENYLOXY DERIVATIVES AND ANTIHYPERLIPIDEMIC USE | BOEHRINGER INGELHEIM GMBH (DT) | 1977-03-01 | — | — | US | disclosed |