Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 14/20 | 0.48 |
| ▸ | CDC25B | P30305 | 12/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.48 |
| ▸ | CDC25A | P30304 | 4/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170857 | 1.00 | PTPN1 (0.48) | PTPN1CDC25BPTPN2CDC25APTPN11 | |
| SCHEMBL12612570 | 0.79 | PTPN1 (0.50) | PTPN1CDC25BPTPN2CDC25APTPN11 | |
| SCHEMBL14001397 | 0.79 | PTPN1 (0.50) | PTPN1CDC25BPTPN2CDC25APTPN11 | |
| SCHEMBL1171495 | 0.76 | PTPN1 (0.53) | PTPN1CDC25BPTPN2CDC25APTPN11 | |
| SCHEMBL15514995 | 0.74 | PTPN1 (0.55) | PTPN1CDC25BPTPN2CDC25APTPN11 | |
| SCHEMBL3462964 | 0.74 | NT5E (0.46) | PTPN1CDC25BPTPN2CDC25APTPN11 | |
| SCHEMBL10314126 | 0.74 | PTPN1 (0.54) | PTPN1CDC25BPTPN2CDC25APTPN11 | |
| SCHEMBL10314144 | 0.74 | PTPN1 (0.54) | PTPN1CDC25BPTPN2CDC25APTPN11 | |
| SCHEMBL10314131 | 0.74 | PTPN1 (0.54) | PTPN1CDC25BPTPN2CDC25APTPN11 | |
| SCHEMBL12869084 | 0.74 | PTPN1 (0.54) | PTPN1CDC25BPTPN2CDC25APTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8211859-B2 | α-galactoceramide analogs, their methods of manufacture, intermediate compounds useful in these methods, and pharmaceutical compositions containing them | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-07-03 | — | — | US | disclosed |
| US-20110028411-A1 | ALPHA-GALACTOCERAMIDE ANALOGS, THEIR METHODS OF MANUFACTURE, INTERMEDIATE COMPOUNDS USEFUL IN THESE METHODS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFQUE (FR) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028411-A1 | ALPHA-GALACTOCERAMIDE ANALOGS, THEIR METHODS OF MANUFACTURE, INTERMEDIATE COMPOUNDS USEFUL IN THESE METHODS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GALE, GALNT14, GALC | PTPN1 4777/4885CDC25B 2094/4885PTPN2 4834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.