Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.73 |
| ▸ | CNR2 | P34972 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4488518 | 0.88 | GAA (0.79) | RAB9ANPC1CNR2TSHRGAA | |
| SCHEMBL4406752 | 0.85 | CNR2 (0.94) | RAB9ANPC1CNR2TSHRDNMT3A | |
| SCHEMBL9312655 | 0.84 | NPC1 (1.00) | RAB9ANPC1TSHRGAACYP3A4 | |
| SCHEMBL4409626 | 0.84 | CNR2 (0.84) | RAB9ANPC1CNR2TSHRGAA | |
| SCHEMBL4411452 | 0.84 | CNR2 (1.00) | RAB9ANPC1CNR2TSHR | |
| SCHEMBL11706684 | 0.83 | RAB9A (0.65) | RAB9ANPC1GAAMAPTMEN1 | |
| SCHEMBL4411536 | 0.83 | CNR2 (0.98) | RAB9ANPC1CNR2TSHR | |
| SCHEMBL4407912 | 0.83 | CNR2 (0.98) | RAB9ANPC1CNR2TSHR | |
| SCHEMBL4414307 | 0.83 | CNR2 (0.72) | RAB9ANPC1CNR2TSHRGAA | |
| SCHEMBL4552004 | 0.83 | CNR2 (0.76) | RAB9ANPC1CNR2TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010279-A | BIPHENYLOXY DERIVATIVES AND ANTIHYPERLIPIDEMIC USE | BOEHRINGER INGELHEIM GMBH (DT) | 1977-03-01 | — | — | US | disclosed |