Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695769 | 0.82 | DHODH (0.44) | GAAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL25053156 | 0.80 | MAPT (0.64) | GAAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL3488590 | 0.79 | ALDH1A1 (0.53) | GAAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL11705225 | 0.77 | POLB (0.57) | GAAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL28202634 | 0.77 | DHODH (0.56) | GAAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL11704342 | 0.77 | MAPT (1.00) | GAAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL23577437 | 0.73 | PDE5A (0.42) | — | |
| SCHEMBL11704650 | 0.73 | MAPT (1.00) | GAAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL6695775 | 0.72 | KMT2A (0.65) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL21933936 | 0.71 | DHODH (0.50) | MAPTALDH1A1KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002755-A | Triazoloquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-01-11 | — | — | US | disclosed |