Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11707394 | 0.88 | POLB (0.40) | FFAR4POLBRXRARXRBRXRG | |
| SCHEMBL11706103 | 0.88 | POLB (0.42) | FFAR4POLBPPARGLMNASELP | |
| SCHEMBL11708826 | 0.86 | FFAR4 (0.44) | FFAR4IMPDH2POLBRXRARXRB | |
| SCHEMBL30888543 | 0.84 | POLB (0.42) | FFAR4POLBPPARGLMNASELP | |
| SCHEMBL4426553 | 0.82 | POLB (0.42) | POLB | |
| SCHEMBL6174574 | 0.80 | PPARA (0.50) | LMNA | |
| SCHEMBL11111891 | 0.80 | POLB (0.50) | FFAR4POLBRXRARXRBRXRG | |
| SCHEMBL12036073 | 0.79 | CYP4F2 (0.49) | POLBLMNA | |
| SCHEMBL7412627 | 0.79 | FFAR4 (0.50) | FFAR4LMNA | |
| SCHEMBL6112808 | 0.78 | PPARA (0.51) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003927-A | DIURETICS | MERCK & CO., INC. (US) | 1977-01-18 | — | — | US | disclosed |