Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | SELP | P16109 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111891 | 0.92 | POLB (0.50) | POLBLMNAFFAR4SMN1; SMN2HSD17B10 | |
| SCHEMBL11709554 | 0.88 | FFAR4 (0.42) | POLBLMNAFFAR4SELPPPARG | |
| SCHEMBL11707394 | 0.88 | POLB (0.40) | POLBLMNAFFAR4SELPSMN1; SMN2 | |
| SCHEMBL28389055 | 0.87 | ALDH1A1 (0.42) | POLBLMNASMN1; SMN2CLCN2 | |
| SCHEMBL30888543 | 0.86 | POLB (0.42) | POLBLMNAFFAR4SELPSMN1; SMN2 | |
| SCHEMBL4426553 | 0.85 | POLB (0.42) | POLBSMN1; SMN2MAPK1PPARAHPGD | |
| SCHEMBL6112808 | 0.83 | PPARA (0.51) | LMNAHDAC1HDAC6PPARA | |
| SCHEMBL6137022 | 0.81 | HSD17B10 (0.56) | POLBSMN1; SMN2HSD17B10CLCN2 | |
| SCHEMBL7412627 | 0.81 | FFAR4 (0.50) | LMNAFFAR4SMN1; SMN2HSD17B10CPT1A | |
| SCHEMBL9717564 | 0.80 | THRB (0.48) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003927-A | DIURETICS | MERCK & CO., INC. (US) | 1977-01-18 | — | — | US | disclosed |