Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.83 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.83 |
| ▸ | MAOB | P27338 | 6/20 | 0.58 |
| ▸ | MAOA | P21397 | 4/20 | 0.58 |
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phentermine SCHEMBL10392295 | 0.91 | SLC6A2 (1.00) | SLC6A2TAAR1MAOBMAOAHTR2A | |
| Phentermine SCHEMBL26615 | 0.91 | SLC6A2 (1.00) | SLC6A2TAAR1MAOBMAOAHTR2A | |
| Phentermine SCHEMBL28695767 | 0.89 | SLC6A2 (0.95) | SLC6A2TAAR1MAOBMAOAHTR2A | |
| Phentermine SCHEMBL3676484 | 0.89 | SLC6A2 (0.95) | SLC6A2TAAR1MAOBMAOAHTR2A | |
| Phentermine SCHEMBL41585 | 0.89 | SLC6A2 (0.95) | SLC6A2TAAR1MAOBMAOAHTR2A | |
| Phentermine SCHEMBL28729624 | 0.89 | SLC6A2 (0.95) | SLC6A2TAAR1MAOBMAOAHTR2A | |
| Phentermine SCHEMBL25214698 | 0.86 | SLC6A2 (0.91) | SLC6A2TAAR1MAOBMAOAHTR2A | |
| Phentermine SCHEMBL677133 | 0.86 | SLC6A2 (0.91) | SLC6A2TAAR1HTR2ASLC6A4HRH1 | |
| Phentermine SCHEMBL29261099 | 0.86 | SLC6A2 (0.91) | SLC6A2TAAR1HTR2ASLC6A4HRH1 | |
| SCHEMBL9467793 | 0.83 | TAAR1 (0.75) | SLC6A2TAAR1HTR2ASLC6A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017543-A | ANTIARRHYTHMIA | MERCK & CO., INC. (US) | 1977-04-12 | — | — | US | disclosed |