Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.40 |
| ▸ | NSD2 | O96028 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786889 | 0.78 | TSHR (0.48) | NR4A2ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL30233483 | 0.78 | TSHR (0.48) | NR4A2ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL10982523 | 0.76 | NOTUM (0.39) | NR4A2TSHRCYP3A4HSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL4725830 | 0.76 | TSHR (0.46) | NR4A2ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL3711871 | 0.74 | HPRT1 (0.52) | ALDH1A1TSHRCYP3A4HPGDHSD17B10 | |
| SCHEMBL3776902 | 0.74 | HPRT1 (0.52) | ALDH1A1TSHRCYP3A4HPGDHSD17B10 | |
| SCHEMBL4659232 | 0.74 | NR4A2 (0.64) | NR4A2ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL21770702 | 0.74 | NR4A2 (0.64) | NR4A2ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL10943366 | 0.74 | NOTUM (0.37) | NOTUMCYP1A2CYP2A6 | |
| SCHEMBL10943367 | 0.74 | PIM1 (0.38) | ALDH1A1TDP1NOTUMKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008326-A | INCREASING PRODUCTION OF PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1977-02-15 | — | — | US | disclosed |