Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4659232 | 0.82 | NR4A2 (0.64) | NR4A2ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL24176053 | 0.78 | ALDH1A1 (0.54) | NR4A2ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL5346560 | 0.78 | NR4A2 (0.59) | NR4A2ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL29932445 | 0.78 | CYP2A6 (0.68) | NR4A2TSHRCYP3A4CYP2A6CYP1A2 | |
| SCHEMBL20356025 | 0.78 | CYP2A6 (0.68) | NR4A2TSHRCYP3A4CYP2A6CYP1A2 | |
| SCHEMBL3183644 | 0.78 | NR4A2 (1.00) | NR4A2ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL29418802 | 0.78 | NR4A2 (1.00) | NR4A2ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL16107418 | 0.77 | ALDH1A1 (0.87) | NR4A2ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL14876644 | 0.77 | ALDH1A1 (0.87) | NR4A2ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL29365003 | 0.77 | ALDH1A1 (1.00) | NR4A2ALDH1A1TSHRCYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827616-B2 | Heterocyclic compounds as pesticides | DISCOVERY PURCHASER CORPORATION (US) | 2023-11-28 | — | — | US | disclosed |
| US-20200062729-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | DISCOVERY PURCHASER CORPORATION | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827616-B2 | Heterocyclic compounds as pesticides | DDT, CHRM1, ACHE | NR4A2 1359/4885ALDH1A1 1236/4885TSHR 377/4885 |
| US-20200062729-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | CHRM1, DDT, ACHE | NR4A2 1073/4885ALDH1A1 1249/4885TSHR 360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.