SCHEMBL11711824

SCHEMBL11711824

Cc1cc(Cl)c(S(N)(=O)=O)cc1C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CISD1 Q9NZ45 11/20 0.72
CA12 O43570 8/20 0.72
CA1 P00915 8/20 0.72
CA2 P00918 8/20 0.72
CA9 Q16790 8/20 0.72
CA4 P22748 6/20 0.72
CA6 P23280 6/20 0.72
CA7 P43166 6/20 0.72
CA13 Q8N1Q1 6/20 0.72
CA14 Q9ULX7 6/20 0.72
CA5B Q9Y2D0 6/20 0.72
CA3 P07451 5/20 0.72
CA5A P35218 3/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7974511 0.84 CISD1 (0.50) CISD1CA12CA1CA2CA9
SCHEMBL6674304 0.84 CISD1 (0.50) CISD1CA12CA1CA2CA9
SCHEMBL31717970 0.84 CA12 (1.00) CISD1CA12CA1CA2CA9
SCHEMBL574023 0.84 CA12 (1.00) CISD1CA12CA1CA2CA9
Hydrochloric Acid SCHEMBL11158505 0.82 CA12 (0.96) CISD1CA12CA1CA2CA9
SCHEMBL11232241 0.82 CISD1 (0.77) CISD1CA12CA1CA2CA9
SCHEMBL11198069 0.81 CISD1 (0.74) CISD1CA12CA1CA2CA9
SCHEMBL8572732 0.81 CA12 (0.71) CISD1CA12CA1CA2CA9
SCHEMBL3040620 0.81 CISD1 (0.74) CISD1CA12CA1CA2CA9
SCHEMBL8572792 0.80 CISD1 (0.68) CISD1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4029787-A Basically substituted 3-sulfamoylbenzoic acid derivatives and process for their preparation HOECHST AKTIENGESELLSCHAFT (DT) 1977-06-14 US disclosed