Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30639142 | 0.86 | RAD52 (0.45) | NR4A1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL6120458 | 0.84 | RAD52 (0.48) | NR4A1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL29527700 | 0.84 | RAD52 (0.48) | NR4A1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL16488065 | 0.81 | RAB9A (0.62) | RAB9AMAPTGAAALDH1A1HTT | |
| SCHEMBL17682914 | 0.80 | RAB9A (0.61) | RAB9AMAPTGAAALDH1A1HTT | |
| SCHEMBL28416831 | 0.80 | RAB9A (0.61) | RAB9AMAPTGAAALDH1A1HTT | |
| SCHEMBL29408378 | 0.80 | RAB9A (0.61) | RAB9AMAPTGAAALDH1A1HTT | |
| SCHEMBL2495024 | 0.79 | NR4A1 (0.61) | NR4A1RAB9AMAPTGAAALDH1A1 | |
| SCHEMBL1290455 | 0.78 | KDM1A (0.58) | NR4A1RAB9AMAPTGAAALDH1A1 | |
| SCHEMBL1290616 | 0.78 | KDM1A (0.58) | NR4A1RAB9AMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001254-A | ISOTHIOCYANOPYRIDINE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |