Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.35 |
| ▸ | NPY1R | P25929 | 7/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11720038 | 0.97 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3ROCK1HTR2C | |
| SCHEMBL11715754 | 0.94 | EED (0.40) | NPY1R | |
| SCHEMBL11713762 | 0.90 | ITGB3 (0.42) | SLC6A2SLC6A4ROCK1ITGB3ITGA2B | |
| SCHEMBL11717587 | 0.90 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3ITGB3ITGA2B | |
| SCHEMBL11716427 | 0.87 | ITGB3 (0.42) | SLC6A2SLC6A4SLC6A3ITGB3ITGA2B | |
| SCHEMBL2890073 | 0.84 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3ITGB3ITGA2B | |
| SCHEMBL11719097 | 0.83 | NPY1R (0.41) | NPY1R | |
| SCHEMBL11716570 | 0.83 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3ROCK1ITGB3 | |
| SCHEMBL11715796 | 0.82 | SLC6A4 (0.36) | SLC6A2SLC6A4SLC6A3HTR2CHTR6 | |
| SCHEMBL11715349 | 0.82 | HTR2C (0.36) | SLC6A2SLC6A4SLC6A3HTR2CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010272-A | ANTHELMINTICALLY ACTIVE BASICALLY SUBSTITUTED 2-CARBALKOXY-AMINO-BENZIMIDAZOLYL-5(6)-PHENYL ETHERS AND -KETONES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | disclosed |