Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK3 | O43781 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11718575 | 0.95 | DYRK3 (0.44) | DYRK3RPS6KB1EPHA2FLT4CSNK2A1 | |
| SCHEMBL11712730 | 0.92 | KMT2A (0.48) | DYRK3RPS6KB1EPHA2FLT4CSNK2A1 | |
| SCHEMBL11715791 | 0.92 | TDP1 (0.47) | DYRK3RPS6KB1EPHA2FLT4CSNK2A1 | |
| SCHEMBL11717040 | 0.90 | KMT2A (0.47) | DYRK3RPS6KB1EPHA2FLT4CSNK2A1 | |
| SCHEMBL11782754 | 0.89 | KMT2A (0.47) | DYRK3RPS6KB1EPHA2FLT4CSNK2A1 | |
| SCHEMBL11714400 | 0.88 | TDP1 (0.48) | DYRK3RPS6KB1EPHA2FLT4CSNK2A1 | |
| SCHEMBL11710100 | 0.87 | TDP1 (0.43) | DYRK3RPS6KB1EPHA2FLT4CSNK2A1 | |
| SCHEMBL11711354 | 0.86 | PRMT1 (0.46) | MAPTKMT2APOLBHTTTDP1 | |
| SCHEMBL11720207 | 0.85 | POLB (0.45) | DYRK3RPS6KB1EPHA2FLT4CSNK2A1 | |
| SCHEMBL11711298 | 0.85 | TDP1 (0.41) | DYRK3RPS6KB1EPHA2FLT4CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |