Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | RGS12 | O14924 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11715791 | 0.95 | TDP1 (0.47) | KMT2ATDP1POLBMAPTHTT | |
| SCHEMBL11720207 | 0.93 | POLB (0.45) | KMT2ATDP1POLBMAPTHTT | |
| SCHEMBL11716330 | 0.93 | KMT2A (0.48) | KMT2ATDP1POLBMAPTHTT | |
| SCHEMBL11712380 | 0.92 | DYRK3 (0.47) | KMT2ATDP1POLBMAPTHTT | |
| SCHEMBL11714400 | 0.91 | TDP1 (0.48) | KMT2ATDP1POLBMAPTHTT | |
| SCHEMBL11710100 | 0.90 | TDP1 (0.43) | KMT2ATDP1POLBMAPTHTT | |
| SCHEMBL11718139 | 0.89 | PRMT1 (0.59) | KMT2ATDP1POLBMAPTHTT | |
| SCHEMBL11711354 | 0.89 | PRMT1 (0.46) | KMT2ATDP1POLBMAPTHTT | |
| SCHEMBL11711298 | 0.88 | TDP1 (0.41) | KMT2ATDP1POLBMAPTHTT | |
| SCHEMBL11722550 | 0.88 | PRMT1 (0.47) | KMT2ATDP1POLBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |