Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25210751 | 0.80 | PTGS1 (0.63) | CYP3A4ALDH1A1POLBNPC1KMT2A | |
| SCHEMBL11713369 | 0.80 | KMT2A (0.60) | CYP3A4ALDH1A1POLBNPC1CYP1A2 | |
| SCHEMBL11720157 | 0.74 | GAA (0.44) | ALDH1A1NPC1KMT2AMEN1TDP1 | |
| SCHEMBL11817513 | 0.72 | PTGS1 (0.67) | CYP3A4ALDH1A1POLBNPC1KMT2A | |
| SCHEMBL11808261 | 0.71 | PTGS1 (0.69) | CYP3A4ALDH1A1POLBNPC1TSHR | |
| SCHEMBL11812310 | 0.70 | PTGS1 (0.56) | CYP3A4ALDH1A1POLBNPC1KMT2A | |
| SCHEMBL11811601 | 0.70 | PTGS1 (0.62) | CYP3A4ALDH1A1POLBNPC1TSHR | |
| SCHEMBL11808596 | 0.69 | PTGS1 (0.75) | ALDH1A1NPC1KMT2AMEN1PTGS1 | |
| SCHEMBL11808813 | 0.69 | PTGS1 (0.61) | CYP3A4ALDH1A1POLBNPC1CYP1A2 | |
| SCHEMBL11806443 | 0.69 | PTGS1 (0.61) | CYP3A4ALDH1A1POLBNPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |