Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CTSD | P07339 | 1/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11713369 | 0.83 | KMT2A (0.60) | PTGS1PTGS2GAAKMT2ATDP1 | |
| SCHEMBL11817513 | 0.82 | PTGS1 (0.67) | PTGS1PTGS2GAAKMT2ATDP1 | |
| SCHEMBL25214021 | 0.81 | PTGS1 (0.58) | PTGS1PTGS2GAAKMT2ATDP1 | |
| SCHEMBL11713363 | 0.80 | CYP3A4 (0.47) | PTGS1PTGS2GAAKMT2ATDP1 | |
| SCHEMBL11808261 | 0.80 | PTGS1 (0.69) | PTGS1PTGS2GAAKMT2AALDH1A1 | |
| SCHEMBL25246486 | 0.80 | PTGS1 (0.69) | PTGS1PTGS2GAAKMT2ATDP1 | |
| SCHEMBL577155 | 0.78 | PTGS1 (1.00) | PTGS1PTGS2GAAKMT2AALDH1A1 | |
| SCHEMBL25213185 | 0.76 | PTGS1 (0.69) | PTGS1PTGS2KMT2AALDH1A1RAB9A | |
| SCHEMBL30423672 | 0.76 | PTGS1 (0.69) | PTGS1PTGS2GAAKMT2ATDP1 | |
| SCHEMBL25210744 | 0.76 | PTGS1 (0.69) | PTGS1PTGS2KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |