SCHEMBL11713610

SCHEMBL11713610

Cc1ccccc1OC(C(=O)O)C(C)C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.46
PPARG P37231 2/20 0.46
PPARA Q07869 2/20 0.46
HPGD P15428 1/20 0.46
MEN1 O00255 1/20 0.45
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
TSHR P16473 5/20 0.43
NOTUM Q6P988 2/20 0.43
CASP1 P29466 1/20 0.42
HTR2A P28223 3/20 0.41
HTR2C P28335 3/20 0.41
HTR2B P41595 3/20 0.41
HTT P42858 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
RXRG P48443 1/20 0.41
CYP1A2 P05177 3/20 0.40
CYP3A4 P08684 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5319081 0.91 KMT2A (0.46) KMT2AHPGDMEN1KDM4EALDH1A1
SCHEMBL555424 0.91 KMT2A (0.46) KMT2AHPGDMEN1KDM4EALDH1A1
SCHEMBL1162259 0.91 KMT2A (0.46) KMT2AHPGDMEN1KDM4EALDH1A1
SCHEMBL1008975 0.84 KDM4E (0.43) KMT2APPARGPPARAHPGDMEN1
SCHEMBL31069134 0.81 KMT2A (0.68) KMT2AHPGDMEN1KDM4EALDH1A1
SCHEMBL8935823 0.81 KMT2A (0.68) KMT2AHPGDMEN1KDM4EALDH1A1
SCHEMBL12310141 0.81 KMT2A (0.68) KMT2AHPGDMEN1KDM4EALDH1A1
SCHEMBL31002548 0.81 KMT2A (0.68) KMT2AHPGDMEN1KDM4EALDH1A1
SCHEMBL830741 0.81 KMT2A (0.68) KMT2AHPGDMEN1KDM4EALDH1A1
SCHEMBL28319743 0.81 PPARG (0.48) KMT2APPARGPPARAHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4056628-A Insecticidal esters of alpha-phenoxy alkanoic acids with substituted benzyl alcohols HOFFMANN-LA ROCHE INC. (US) 1977-11-01 US disclosed