Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31002548 | 1.00 | KMT2A (0.68) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL31069134 | 1.00 | KMT2A (0.68) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL830741 | 1.00 | KMT2A (0.68) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL12310141 | 1.00 | KMT2A (0.68) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL1626832 | 0.85 | HPGD (0.55) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL2058985 | 0.83 | HPGD (0.54) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL7077662 | 0.83 | HPGD (0.54) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL555424 | 0.82 | KMT2A (0.46) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL1162259 | 0.82 | KMT2A (0.46) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL9423878 | 0.82 | KMT2A (0.46) | KMT2ATSHRHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |