Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 2/20 | 0.31 |
| ▸ | HPN | P05981 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.31 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11141268 | 0.93 | PTGS1 (0.36) | PTGS1PTGS2CA1CA2GAA | |
| SCHEMBL11182464 | 0.89 | PTGS1 (0.36) | PTGS1PTGS2CA1CA2SMN1; SMN2 | |
| SCHEMBL8065729 | 0.89 | PTGS1 (0.36) | PTGS1PTGS2CA1CA2SMN1; SMN2 | |
| SCHEMBL11173085 | 0.89 | PTGS1 (0.36) | PTGS1PTGS2CA1CA2SMN1; SMN2 | |
| SCHEMBL11172099 | 0.89 | PTGS1 (0.36) | PTGS1PTGS2CA1CA2SMN1; SMN2 | |
| SCHEMBL11169685 | 0.84 | PTGS1 (0.36) | PTGS1PTGS2CA1CA2SMN1; SMN2 | |
| SCHEMBL11174053 | 0.84 | PTGS1 (0.36) | PTGS1PTGS2CA1CA2SMN1; SMN2 | |
| SCHEMBL11713619 | 0.82 | CA1 (0.33) | PTGS1PTGS2CA1CA2HPN | |
| SCHEMBL11176405 | 0.82 | CA1 (0.40) | PTGS1PTGS2CA1CA2SMN1; SMN2 | |
| SCHEMBL39436 | 0.82 | CA1 (0.40) | PTGS1PTGS2CA1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3960809-A | POLYMERS | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | claimed |
| US-4001181-A | ACTINIC RADIATION STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |