SCHEMBL8065729

SCHEMBL8065729

CCCCCCCCSCCSc1nc(Oc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)nc(Oc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)n1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 5/20 0.36
▸ PTGS2 P35354 5/20 0.36
▸ CA1 P00915 1/20 0.36
▸ CA2 P00918 1/20 0.36
▸ HPN P05981 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ SIRT5 Q9NXA8 1/20 0.33
▸ GPR84 Q9NQS5 7/20 0.33
▸ PTGES O14684 2/20 0.33
▸ CCNE1 P24864 1/20 0.32
▸ CDK2 P24941 1/20 0.32
▸ VCAM1 P19320 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11173085 1.00 PTGS1 (0.36) PTGS1PTGS2CA1CA2HPN
SCHEMBL11182464 0.98 PTGS1 (0.36) PTGS1PTGS2CA1CA2HPN
SCHEMBL11172099 0.98 PTGS1 (0.36) PTGS1PTGS2CA1CA2HPN
SCHEMBL11169685 0.95 PTGS1 (0.36) PTGS1PTGS2CA1CA2HPN
SCHEMBL11174053 0.93 PTGS1 (0.36) PTGS1PTGS2CA1CA2HPN
SCHEMBL39436 0.93 CA1 (0.40) PTGS1PTGS2CA1CA2HPN
SCHEMBL11863295 0.93 CA1 (0.40) PTGS1PTGS2CA1CA2HPN
SCHEMBL11176405 0.93 CA1 (0.40) PTGS1PTGS2CA1CA2HPN
SCHEMBL11170888 0.93 CA1 (0.40) PTGS1PTGS2CA1CA2HPN
SCHEMBL11713623 0.89 PTGS1 (0.34) PTGS1PTGS2CA1CA2HPN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3960809-A POLYMERS CIBA-GEIGY CORPORATION (US) 1976-06-01 — — US claimed
EP-0902853-B1 THERMALLY STABLE ACOUSTICAL INSULATION MINNESOTA MINING & MFG (US) 2000-05-24 — — EP disclosed
US-5961904-A Method of making a thermally stable acoustical insulation microfiber web MINNESOTA MINING AND MANUFACTURING CO. (US) 1999-10-05 — — US disclosed
US-5773375-A MELT BLOWN POLYPROPYLENE WEB, FOR AUTOMOBILES MINNESOTA MINING AND MANUFACTURING COMPANY 1998-06-30 — — US disclosed
US-RE31343-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 — — US disclosed
US-RE31342-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 — — US disclosed
US-4238575-A POLYALKYLTHIOETHYL METHACRYLATE, POLYOLEFINS CIBA-GEIGY CORPORATION (US) 1980-12-09 — — US disclosed
US-4233208-A OXIDATION RESISTANCE, RADIATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1980-11-11 — — US disclosed
US-4219464-A Hindered piperidine carboxylic acids, metal salts thereof and stabilized compositions CIBA-GEIGY CORPORATION (US) 1980-08-26 — — US disclosed
US-4208522-A POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1980-06-17 — — US disclosed
US-3991012-A AGAINST ULTRAVIOLET DETERIORATION OF POLYMERS CIBA-GEIGY CORPORATION (US) 1976-11-09 — — US disclosed
US-3979360-A Compositions stabilized with benzoyloxybenzamides CIBA-GEIGY CORPORATION (US) 1976-09-07 — — US disclosed
US-3969316-A 3,5-Dialkyl-4-hydroxyphenylalkyl substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1976-07-13 — — US disclosed
US-3968078-A Alkyl alkanoate derivatives of substituted piperazine-diones and polymer compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1976-07-06 — — US disclosed
US-3960809-A POLYMERS CIBA-GEIGY CORPORATION (US) 1976-06-01 — — US disclosed
US-3943102-A Compositions stabilized with polyol esters of benzoyloxybenzoic acids CIBA-GEIGY CORPORATION (US) 1976-03-09 — — US disclosed
US-3941746-A Containing hindered phenolic norbornane-2,3-dicarboximides stabilized compositions CIBA-GEIGY CORPORATION (US) 1976-03-02 — — US disclosed
US-3939163-A Metal salts of hindered piperidine carboxylic acids and stabilized compositions CIBA-GEIGY CORPORATION (US) 1976-02-17 — — US disclosed
US-3937711-A POLYMERIC STABILIZERS, POLYOLEFINS CIBA-GEIGY CORPORATION (US) 1976-02-10 — — US disclosed
US-3936456-A Substituted piperazine dione oxyls and hydroxides and polymer compositions stabilized thereby CIBY-GEIGY CORPORATION (US) 1976-02-03 — — US disclosed
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