Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | VNN1 | O95497 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28266082 | 0.83 | CA1 (0.78) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL12294447 | 0.83 | CA1 (0.78) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL16420890 | 0.81 | CYP4A11 (0.50) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL18423580 | 0.80 | VNN1 (0.48) | CA1CA2VNN1POLBMAPT | |
| SCHEMBL10740531 | 0.80 | KMT2A (0.48) | KMT2APOLBMAPTALDH1A1MCHR1 | |
| SCHEMBL18423582 | 0.80 | CA1 (0.47) | CA1CA2MEN1KMT2AVNN1 | |
| SCHEMBL18424233 | 0.80 | CA1 (0.54) | CA1CA2MEN1KMT2AVNN1 | |
| SCHEMBL15878323 | 0.79 | MAPK1 (0.57) | CA1CA2KMT2APOLBMAPT | |
| SCHEMBL10463138 | 0.79 | MCHR1 (0.56) | POLBMCHR1 | |
| SCHEMBL22120004 | 0.79 | MAPK1 (0.57) | CA1CA2KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009174-A | VASODILATORS | THE BOOTS COMPANY LIMITED (EN) | 1977-02-22 | — | — | US | disclosed |