VNN1

Pantetheinase · O95497 · VNN1 on Sugi Atlas →

28,769 patent compounds predicted against VNN1, 11,655 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL507406	0.53	17/20
Pantothenic Acid (SCHEMBL482266)	0.61	13/20
Pantothenic Acid, Racemic (SCHEMBL482267)	0.61	13/20
Pantothenic Acid (SCHEMBL5436)	0.61	13/20
Pantothenic Acid, Racemic (SCHEMBL5437)	0.61	13/20
Pantothenic Acid (SCHEMBL21547)	0.61	13/20
Pantothenic Acid (SCHEMBL34429)	0.59	13/20
Pantothenic Acid (SCHEMBL124922)	0.59	13/20
Pantothenic Acid (SCHEMBL593558)	0.59	13/20
Pantothenic Acid, Racemic (SCHEMBL888199)	0.59	13/20
Pantothenic Acid (SCHEMBL1116386)	0.59	13/20
SCHEMBL482268	0.59	13/20
Pantothenic Acid (SCHEMBL1261506)	0.58	13/20
Pantothenic Acid, Racemic (SCHEMBL1261508)	0.58	13/20
SCHEMBL574067	0.57	13/20
Pantothenic Acid (SCHEMBL34427)	0.55	13/20
Pantothenic Acid (SCHEMBL34428)	0.55	13/20
Pantothenic Acid (SCHEMBL124920)	0.55	13/20
Pantothenic Acid (SCHEMBL124921)	0.55	13/20
Pantothenic Acid (SCHEMBL593556)	0.55	13/20

Clinical trials — most relevant to VNN1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Clinical and Genetic Analysis of Enlarged Vestibular Aqueducts	nan	COMPLETED
Genetic Studies of Lysosomal Storage Disorders	nan	ENROLLING_BY_INVITATION
Characteristics of Idiopathic Familial Voice Disorders	nan	COMPLETED
Study of Usher Syndromes, Type 1 and Type 2	nan	COMPLETED
Using Next-generation Sequencing in the Diagnosis of Epilepsy and/or Intellectual Disability in a Pediatric Cohorte	nan	COMPLETED
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients	nan	RECRUITING
Genetic Analysis of Hereditary Disorders of Hearing and Balance	nan	COMPLETED
Natural History of Neuronal Ceroid Lipofuscinosis, Batten's CLN6 Diseae	nan	ACTIVE_NOT_RECRUITING
Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS) DNA and Tissue Bank	nan	COMPLETED
Genome Environment Microbiome and Metabolome in Autism Study	nan	COMPLETED
Gene Modifiers of Cystic Fibrosis Lung Disease	nan	ACTIVE_NOT_RECRUITING
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network	nan	RECRUITING
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis	nan	COMPLETED
New Strategies of Genetic Study of Patients With Oculocutaneous Albinism	nan	COMPLETED
Genetic Basis of Non Syndromic Congenital Diaphragmatic Hernia	nan	COMPLETED
Testing Drug Efficacy in Cystic Fibrosis Through N-of-1 Trials	nan	RECRUITING
Neonatal Screening of Biotinidase Deficiency: Genotype-phenotype Correlation and Clinical Follow-up	nan	RECRUITING
Genotype-phenotype Correlation Study of Presymptomatic and Symptomatic DFNA9 Patients	nan	RECRUITING
Genetic Disorders of Mucociliary Clearance in Nontuberculous Mycobacterial Lung Disease	nan	COMPLETED
Modeling DNA Diversity in Reverse Cholesterol Transport	nan	COMPLETED
Genetic Response to Warfarin in Healthy Subjects	nan	COMPLETED
Pharmacogenomic Response to Thyrotropin-Releasing Hormone Stimulation in Healthy Volunteers: The Influence of a Common Type 2 Deiodinase Genetic Polymorphism on Serum T3	nan	COMPLETED
Environmental & Genetic Influences on Vitamin D Status	nan	COMPLETED
Immunogenetic Modulators of Mucosal Protection From HIV-1	nan	COMPLETED
Genetic Analysis of Familial Melanoma	nan	COMPLETED
Identification of New Genes Implicated in Rare Neurosensory Diseases by Whole Exome Sequencing	nan	UNKNOWN
Diffusion Tensor Imaging (DTI) in Infants With Krabbe Disease	nan	ACTIVE_NOT_RECRUITING
Genetic Predictors of Lithium Response in Bipolar Disorder	nan	COMPLETED
Lipa Gene Mutation in PED-LIPIGEN (Pediatric FH Subjects)	nan	UNKNOWN
Frequency of Pompe Disease in Patients With Myalgia With or Without Hyper Ckemia - Data From the Reference Center (CERCA)	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a VNN1 binder may also engage these)

Protein	Name	Similarity
O95498	—	0.999	O95498 →
Q9QZ25	—	0.999	Q9QZ25 →
Q9TSX8	—	0.998	Q9TSX8 →
Q9BDJ5	—	0.994	Q9BDJ5 →
Q58CQ9	—	0.993	Q58CQ9 →
Q9Z0K8	—	0.992	Q9Z0K8 →
A6QQ07	—	0.990	A6QQ07 →
Q5FVF9	—	0.988	Q5FVF9 →
Q8AV84	—	0.983	Q8AV84 →
Q8CIF4	—	0.978	Q8CIF4 →
W8E7D1	—	0.978	W8E7D1 →
J3SBP3	—	0.976	J3SBP3 →
Q5R8R3	—	0.975	Q5R8R3 →
P18563	—	0.975	P18563 →
P15396	—	0.974	P15396 →
Q8BG22	—	0.973	Q8BG22 →
Q9SYL6	—	0.973	Q9SYL6 →
Q9CQF9	—	0.972	Q9CQF9 →
P0DQQ4	—	0.972	P0DQQ4 →
BTD	Biotinidase	0.972	landscape →
Q6DYE8	—	0.972	Q6DYE8 →
A5PJN5	—	0.972	A5PJN5 →
ENPP3	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3	0.971	landscape →
Q5R5M5	—	0.971	Q5R5M5 →
P52787	—	0.971	P52787 →
Q9R1Q9	—	0.971	Q9R1Q9 →
A2A863	—	0.971	A2A863 →
Q9JJF9	—	0.970	Q9JJF9 →
Q29052	—	0.970	Q29052 →
P26008	—	0.970	P26008 →