Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4880191 | 0.74 | CTSB (0.55) | MEN1MAPTKMT2AKDM4ELMNA | |
| SCHEMBL30064912 | 0.74 | CTSB (0.55) | MEN1MAPTKMT2AKDM4ELMNA | |
| SCHEMBL26654465 | 0.74 | CTSB (0.42) | MEN1MAPTKMT2AKDM4ELMNA | |
| SCHEMBL11232707 | 0.73 | CTSB (0.44) | MEN1MAPTKMT2AKDM4ELMNA | |
| SCHEMBL9861634 | 0.72 | KDM4E (0.54) | MEN1MAPTKMT2AKDM4ELMNA | |
| SCHEMBL19284577 | 0.71 | IDO1 (0.38) | MEN1MAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL31279653 | 0.71 | CA1 (0.42) | LMNAMAPK1SMN1; SMN2IDO1POLB | |
| SCHEMBL459134 | 0.71 | CA1 (0.42) | LMNAMAPK1SMN1; SMN2IDO1POLB | |
| SCHEMBL9990219 | 0.69 | EP300 (0.48) | MEN1MAPTKMT2AKDM4ELMNA | |
| SCHEMBL3267567 | 0.69 | CTSB (0.42) | MEN1MAPTKMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008326-A | INCREASING PRODUCTION OF PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1977-02-15 | — | — | US | disclosed |