Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713795 | 1.00 | CYP1A2 (0.67) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL4651678 | 1.00 | CYP1A2 (0.67) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL24805728 | 0.94 | CYP1A2 (0.61) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL21992740 | 0.94 | CYP1A2 (0.61) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL11180474 | 0.94 | CYP1A2 (0.61) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL4262556 | 0.91 | CYP1A2 (0.77) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| Toluene SCHEMBL28734442 | 0.86 | CYP1A2 (0.65) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL11550164 | 0.85 | CYP1A2 (0.69) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL8900988 | 0.85 | CYP1A2 (0.69) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL5803914 | 0.84 | PPARG (0.52) | CYP1A2GAACYP2C9PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716159-B1 | BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2011-07-13 | — | — | EP | claimed |
| EP-1971222-A2 | REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS | GENERAL MILLS, INC. (US) | 2008-09-24 | — | — | EP | claimed |
| EP-1697386-B1 | ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES | GEN ELECTRIC (US) | 2007-10-10 | — | — | EP | claimed |
| WO-2007059066-A2 | REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS | GENERAL MILLS, INC. (US) | 2007-05-24 | — | — | WO | claimed |
| US-20070110844-A1 | REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS | GENERAL MILLS, INC. | 2007-05-17 | — | — | US | claimed |
| EP-0159864-B1 | METHOD OF MODIFYING TASTE | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1989-07-19 | — | — | EP | claimed |
| EP-0159864-A2 | Method of modifying taste | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1985-10-30 | — | — | EP | claimed |
| EP-4378938-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2024-06-05 | — | — | EP | disclosed |
| US-11932653-B2 | Lycorine derivative, and pharmaceutical composition and use thereof | SHANDONG DYNE MARINE BIOPHARMACEUTICAL CO., LTD (CN) | 2024-03-19 | — | — | US | disclosed |
| CN-117645540-A | Preparation method of chlorophenoxycarboxylate | 山东润博生物科技有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-117642393-A | Novel PARP7 inhibitor and application thereof | 上海齐鲁制药研究中心有限公司 | 2024-03-01 | — | — | CN | disclosed |
| EP-3470407-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2024-01-24 | — | — | EP | disclosed |
| US-20240009169-A9 | PPARG Modulators for the Treatment of Osteoporosis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2024-01-11 | — | — | US | disclosed |
| US-5045336-A | Reducing sweet taste of high sugar foods, organic acids and acid salts | AMSTAR SUGAR CORPORATION (US) | 1991-09-03 | — | — | US | disclosed |
| EP-0159864-B1 | METHOD OF MODIFYING TASTE | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1989-07-19 | — | — | EP | disclosed |
| CN-88100219-A | New carboxylic acid derivative and preparation technology thereof and the medicinal compositions that contains these derivatives | — | 1988-07-27 | — | — | CN | disclosed |
| EP-0159864-A2 | Method of modifying taste | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1985-10-30 | — | — | EP | disclosed |
| EP-0068295-A1 | A new herbicidal composition, processes for its production and its use | A. Nattermann & Cie. GmbH (DE) | 1983-01-05 | — | — | EP | disclosed |
| US-4252961-A | Intermediates of and process for making 3-[5-[1-(2-, 3-, or 4-methyl, or ethyl or isopropylphenoxy)alkyl, alkynyl, alkenyl, or haloalkyl]-1,3,4-thiadiazol-2-yl]-4-hydroxy-1-methyl-2-imidazolidinones | PPG INDUSTRIES, INC. (US) | 1981-02-24 | — | — | US | disclosed |
| US-4218236-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | PPG INDUSTRIES, INC. (US) | 1980-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11932653-B2 | Lycorine derivative, and pharmaceutical composition and use thereof | LCT, LARP7, LASP1 | CYP1A2 2479/4885GAA 311/4885CYP2C9 550/4885 |
| US-20240009169-A9 | PPARG Modulators for the Treatment of Osteoporosis | PPARG, PPARA, PPARD | CYP1A2 3409/4885GAA 3259/4885CYP2C9 3963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.