Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.63 |
| ▸ | CNR1 | P21554 | 6/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11354858 | 0.90 | CNR2 (0.52) | CNR2CNR1TRPA1CYP1A1CYP1A2 | |
| SCHEMBL11634391 | 0.88 | CNR2 (0.51) | CNR2CNR1 | |
| SCHEMBL11716511 | 0.84 | CNR2 (0.62) | CNR2CNR1TRPA1CYP1A1CYP1A2 | |
| SCHEMBL11717962 | 0.83 | CNR2 (0.64) | CNR2CNR1TRPA1CYP1A1CYP1A2 | |
| SCHEMBL14456000 | 0.83 | CNR2 (0.45) | CNR2 | |
| SCHEMBL11636529 | 0.83 | CNR2 (0.65) | CNR2CNR1TRPA1CYP1A1CYP1A2 | |
| SCHEMBL11717451 | 0.83 | CNR2 (0.65) | CNR2CNR1TRPA1CYP1A1CYP1A2 | |
| SCHEMBL11354855 | 0.82 | CNR2 (0.43) | CNR2CNR1 | |
| SCHEMBL11642448 | 0.82 | CNR2 (0.67) | CNR2CNR1TRPA1CYP1A1CYP1A2 | |
| SCHEMBL11837940 | 0.82 | CNR2 (0.52) | CNR2CNR1TRPA1CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042694-A | ANALGESICS | SHARPS ASSOCIATES (US) | 1977-08-16 | — | — | US | disclosed |
| US-4025630-A | Anesthesia methods using benzopyrans and esters thereof as pre-anesthesia medication | ABBOTT LABORATORIES (US) | 1977-05-24 | — | — | US | disclosed |
| US-3991194-A | Heterocyclic esters of benzopyranopyridines | SHARPS ASSOCIATES (US) | 1976-11-09 | — | — | US | disclosed |