Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | RGS12 | O14924 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329310 | 0.84 | CYP1B1 (0.53) | CYP1B1PRMT1MAPTHTTKMT2A | |
| SCHEMBL11709021 | 0.83 | PRMT1 (0.46) | CYP1B1PRMT1MAPTHTTKMT2A | |
| SCHEMBL11718867 | 0.82 | PRMT1 (0.52) | CYP1B1PRMT1MAPTHTTKMT2A | |
| SCHEMBL9169702 | 0.82 | TYMS (0.48) | CYP1B1MAPTKMT2AMEN1POLB | |
| SCHEMBL11718152 | 0.81 | PRMT1 (0.44) | CYP1B1PRMT1MAPTHTTKMT2A | |
| SCHEMBL11718393 | 0.80 | PRMT1 (0.50) | CYP1B1PRMT1MAPTHTTKMT2A | |
| SCHEMBL11716566 | 0.79 | PRMT1 (0.49) | CYP1B1PRMT1MAPTHTTKMT2A | |
| SCHEMBL11719230 | 0.78 | PRMT1 (0.52) | CYP1B1PRMT1MAPTHTTKMT2A | |
| SCHEMBL11709886 | 0.78 | PRMT1 (0.49) | CYP1B1PRMT1MAPTHTTKMT2A | |
| SCHEMBL11714317 | 0.77 | PRMT1 (0.74) | CYP1B1PRMT1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |