Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.56 |
| ▸ | TSHR | P16473 | 9/20 | 0.56 |
| ▸ | HPGD | P15428 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29472174 | 0.80 | ALDH1A1 (0.53) | HSD17B10TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL1156294 | 0.79 | CA9 (0.44) | HSD17B10TSHRHPGDALDH1A1CYP3A4 | |
| Fluoride SCHEMBL28376895 | 0.77 | ALDH1A1 (0.50) | HSD17B10TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL26092481 | 0.75 | CA9 (0.36) | HSD17B10TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL21979280 | 0.75 | CA9 (0.36) | HSD17B10TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL23832925 | 0.75 | HPGD (0.37) | HSD17B10TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL30412164 | 0.75 | CA9 (0.36) | HSD17B10TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL23205868 | 0.75 | CYP3A4 (0.48) | HSD17B10TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL374815 | 0.75 | HSD17B10 (0.58) | HSD17B10TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL7785639 | 0.72 | HSD17B10 (0.72) | HSD17B10TSHRHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060562-A | SULFUR CONTAINING CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-29 | — | — | US | disclosed |