SCHEMBL11715352

SCHEMBL11715352

O=S(=O)(O)c1ccc2cc3ccccc3cc2c1-c1nc(Cl)nc(Cl)n1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 1/20 0.35
MPL P40238 3/20 0.35
CTRC Q99895 2/20 0.35
KAT6A Q92794 4/20 0.34
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
CYP1A2 P05177 2/20 0.32
HIF1A Q16665 2/20 0.32
HSD17B10 Q99714 2/20 0.32
CYP2C9 P11712 1/20 0.32
ALOX15 P16050 1/20 0.32
ATIC P31939 1/20 0.32
CYP2C19 P33261 1/20 0.32
CYP2D6 P10635 1/20 0.32
RCE1 Q9Y256 1/20 0.32
NR4A1 P22736 1/20 0.31
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL30109021 0.75 CYP2D6 (0.45) CTRB1MPLCTRCALDH1A1KDM4E
SCHEMBL30108870 0.73 CYP2D6 (0.46) CTRB1MPLCTRCALDH1A1KDM4E
SCHEMBL151653 0.73 CYP2D6 (0.46) CTRB1MPLCTRCALDH1A1KDM4E
SCHEMBL17212147 0.72 CYP2A6 (0.39) MPLCTRCALDH1A1KDM4EGAA
SCHEMBL10343282 0.72 TTR (0.47) ALDH1A1KDM4EGAAHSD17B10CYP2C9
SCHEMBL686314 0.72 CYP2D6 (0.45) CTRB1MPLCTRCALDH1A1KDM4E
Ammonia Solution, Strong SCHEMBL28934766 0.71 NR4A1 (0.50) CTRB1MPLCTRCALDH1A1KDM4E
Ammonia Solution, Strong SCHEMBL3630747 0.71 CTRB1 (0.51) CTRB1MPLCTRCALDH1A1CYP1A2
SCHEMBL28019471 0.70 CTRB1 (0.41) CTRB1MPLCTRCALDH1A1KDM4E
Ammonia Solution, Strong SCHEMBL27988344 0.70 NR4A1 (0.49) CTRB1MPLCTRCALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4054559-A Reactive disazo monohalogenotriazine dyestuffs NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1977-10-18 US disclosed