Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11713217 | 0.97 | SLC6A3 (0.44) | SLC6A3SMN1; SMN2NPSR1 | |
| SCHEMBL11712930 | 0.91 | SLC6A3 (0.39) | SLC6A3HTT | |
| SCHEMBL11716096 | 0.88 | SLC6A3 (0.43) | SLC6A3 | |
| SCHEMBL28380363 | 0.85 | ELANE (0.46) | SLC6A3ALDH1A1LMNA | |
| SCHEMBL11712045 | 0.85 | SLC6A3 (0.41) | SLC6A3SMN1; SMN2LTA4H | |
| SCHEMBL11714559 | 0.83 | SLC6A3 (0.43) | SLC6A3 | |
| SCHEMBL11717919 | 0.82 | SLC6A3 (0.38) | SLC6A3ALDH1A1LMNA | |
| SCHEMBL11717552 | 0.82 | NR4A1 (0.45) | SLC6A3LTA4H | |
| SCHEMBL11711829 | 0.79 | SLC6A3 (0.41) | SLC6A3ALDH1A1LMNA | |
| SCHEMBL5317949 | 0.79 | PARP10 (0.51) | SLC6A3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010272-A | ANTHELMINTICALLY ACTIVE BASICALLY SUBSTITUTED 2-CARBALKOXY-AMINO-BENZIMIDAZOLYL-5(6)-PHENYL ETHERS AND -KETONES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | disclosed |