Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nabitan SCHEMBL31402797 | 0.93 | — | — | |
| Nabitan SCHEMBL122778 | 0.92 | — | — | |
| SCHEMBL11716868 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL11721730 | 0.92 | CNR1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL11722541 | 0.90 | — | — | |
| SCHEMBL11715005 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL11714157 | 0.89 | — | — | |
| Bromide SCHEMBL11717532 | 0.88 | CNR2 (0.36) | — | |
| SCHEMBL11810940 | 0.87 | CNR2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL11387553 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042694-A | ANALGESICS | SHARPS ASSOCIATES (US) | 1977-08-16 | — | — | US | disclosed |
| US-4025630-A | Anesthesia methods using benzopyrans and esters thereof as pre-anesthesia medication | ABBOTT LABORATORIES (US) | 1977-05-24 | — | — | US | disclosed |
| US-3991194-A | Heterocyclic esters of benzopyranopyridines | SHARPS ASSOCIATES (US) | 1976-11-09 | — | — | US | disclosed |