Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11863406 | 0.93 | CNR2 (0.37) | CNR2CNR1 | |
| SCHEMBL11716871 | 0.92 | CNR2 (0.37) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL11371812 | 0.92 | CNR2 (0.37) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL11721734 | 0.92 | CNR2 (0.36) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL11722553 | 0.90 | CNR2 (0.36) | CNR2CNR1 | |
| SCHEMBL11715013 | 0.90 | CNR2 (0.38) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL11714160 | 0.89 | CNR2 (0.37) | CNR2CNR1 | |
| Bromide SCHEMBL11717524 | 0.88 | — | — | |
| SCHEMBL11810951 | 0.87 | CNR2 (0.40) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL11813313 | 0.87 | CNR2 (0.39) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042694-A | ANALGESICS | SHARPS ASSOCIATES (US) | 1977-08-16 | — | — | US | disclosed |
| US-3991194-A | Heterocyclic esters of benzopyranopyridines | SHARPS ASSOCIATES (US) | 1976-11-09 | — | — | US | disclosed |