Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA7 | P43166 | 4/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA4 | P22748 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544198 | 0.91 | KDM4E (0.58) | KDM4EHSD17B10USP2ALDH1A1LMNA | |
| SCHEMBL11543513 | 0.89 | KDM4E (0.59) | KDM4EHSD17B10USP2ALDH1A1LMNA | |
| SCHEMBL11543455 | 0.88 | KDM4E (0.60) | KDM4EHSD17B10USP2ALDH1A1LMNA | |
| SCHEMBL10281400 | 0.87 | KDM4E (0.61) | KDM4EHSD17B10USP2ALDH1A1LMNA | |
| SCHEMBL11548236 | 0.81 | KDM4E (0.51) | KDM4EHSD17B10USP2ALDH1A1LMNA | |
| SCHEMBL11542663 | 0.78 | KDM4E (0.53) | KDM4EHSD17B10USP2ALDH1A1LMNA | |
| SCHEMBL11547152 | 0.78 | KDM4E (0.53) | KDM4EHSD17B10USP2ALDH1A1LMNA | |
| SCHEMBL10281398 | 0.77 | ALDH1A1 (0.51) | KDM4EHSD17B10USP2ALDH1A1LMNA | |
| SCHEMBL11717707 | 0.76 | KDM4E (0.45) | KDM4EHSD17B10USP2ALDH1A1LMNA | |
| SCHEMBL11543237 | 0.76 | ALDH1A1 (0.45) | KDM4EHSD17B10USP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010273-A | DIURETICS, SALURETICS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | disclosed |