Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 10/20 | 0.54 |
| ▸ | BCL2 | P10415 | 8/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11712238 | 0.90 | PRMT1 (0.49) | MCL1BCL2PRMT1KMT2AKDM4E | |
| SCHEMBL11717408 | 0.89 | MCL1 (0.47) | MCL1BCL2PRMT1KMT2AKDM4E | |
| SCHEMBL11717142 | 0.86 | PRMT1 (0.70) | MCL1BCL2PRMT1KMT2AKDM4E | |
| SCHEMBL11719602 | 0.84 | PRMT1 (0.56) | MCL1BCL2PRMT1KMT2AKDM4E | |
| SCHEMBL11720545 | 0.84 | PRMT1 (0.44) | MCL1BCL2PRMT1KMT2AKDM4E | |
| SCHEMBL11718202 | 0.82 | BCL2 (0.55) | MCL1BCL2PRMT1KMT2AKDM4E | |
| SCHEMBL11716007 | 0.77 | PRMT1 (0.50) | PRMT1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL11717636 | 0.77 | PRMT1 (0.50) | PRMT1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL11716769 | 0.77 | BCL2 (0.50) | MCL1BCL2PRMT1KMT2AKDM4E | |
| SCHEMBL11713392 | 0.77 | PRMT1 (0.50) | PRMT1KMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |